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Lab Dog

What Global Science Owes American Beagles

Lab Dog

What Global Science Owes American Beagles

Tracing over a century of transformation in the relationship between humans and our “best friend,” from hunting companion to laboratory commodity to modern pet.
 
Intrepid, docile, and cloaked in their characteristic coats of white, black, and tan, beagles were one of the most popular breeds in the United States by 1950. But during the same period, they emerged as something else: an ideal dog for laboratory experimentation. After researchers used the breed to test the effects of radiation exposure, scientists looking for subjects larger and longer-living than rodents began to turn to beagles, who were loyal, cooperative, and eager to please.
 
In Lab Dog, historian Brad Bolman explains how the laboratory dog became a subject of intense focus for twentieth-century scientists and charts the beagle’s surprising trajectory through global science. Following beagles as they moved from eugenics to radiobiology, pharmaceutical testing to Alzheimer’s studies, Lab Dog sheds new light on pivotal stories of twentieth-century science, including the Manhattan Project, tobacco controversies, contraceptive testing, and behavioral genetics research. Bolman shows how these experiments evolved alongside our understanding of dogs, revealing why we now see them as intelligent companions who deserve moral protection and socialization—and in some cases, special food or daily medication. The book also offers a glimpse into the future of animal experimentation, one in which dogs are increasingly replaced by other species, as well as non-animal alternatives. Compelling and accessible, Lab Dog tells the thorny story of the beagle’s participation in science, both its sacrifice and its contribution.

See a website for the book. 


376 pages | 7 halftones | 6 x 9 | © 2025

Biological Sciences: Behavioral Biology

History of Science

Medicine

Reviews

“This isn’t just a book for the beagle obsessed: Bolman has found something for everyone fascinated by our most ancient friendship in the animal kingdom. Laboratory dogs may be a side of the human-canine relationship that most people would prefer not to think about, but Bolman has a knack for finding stones others in the ever-growing literature on dogs had not thought to turn over and mixes the uplifting and the macabre with a light touch. He takes the reader from ancient hunting hounds to modern lab dogs by way of eugenics, Snoopy, the Atomic Energy Commission’s appallingly named ‘Project Hot Dog,’ and beagles’ role in the battle to prove smoking causes lung cancer. The result fascinates, entertains, and gives pause to contemplate man’s inhumanity to hound in equal measure.”

Clive D. L. Wynne, author of “Dog Is Love: Why and How Your Dog Loves You”

Lab Dog offers a comprehensive, insightful, and sympathetic account of the transformation of the beagle from a sporting and pet breed into an experimental model or tool. Bolman has addressed a difficult topic: his detailed descriptions of experimental procedures are often dismaying, along with his discussion of the mass production of beagles for what became an international scientific and pharmacological supply chain. But these vivid and clearsighted evocations are part of what makes his analysis so persuasive.”

Harriet Ritvo, author of “Noble Cows and Hybrid Zebras: Essays on Animals and History”

Table of Contents

Preface
Introduction
1: A New Breed of Science: American Beagles, Eugenics, and National Fantasies
2: Atomic Dogs: Cold War Anxieties, Normal Animals, and the Uses of Care
3: Dog Times and Lifetimes: Beagle Commodities, Computers, and the Drug-Using Body
4: Hot and Smoking Dogs: Cigarettes, Emotions, and Ignorance
5: The Age of Dogs: Cognitive Dysfunction, Canine Pharmaceuticals, and Companion Science
Conclusion: The Ends of Beagle Science
Acknowledgments
Notes
Index

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