The ABC of Acid-Base Chemistry
The Elements of Physiological Blood-Gas Chemistry for Medical Students and Physicians
Sixth Edition
9780226137032
The ABC of Acid-Base Chemistry
The Elements of Physiological Blood-Gas Chemistry for Medical Students and Physicians
Sixth Edition
The ABC of Acid-Base Chemistry provides physiologists, medical students, and physicians with an intelligible outline of the elements of physiological acid-base chemistry.
This new edition of Horace W. Davenport’s standard text takes into account different ways of looking at the problems of acid-base derived from new instrumentation. The exposition has been modified to allow the student to apply his understanding to other systems of description of the acid-base status. Although the pH system has been retained, there is increasing emphasis on the use of hydrogen ion concentration.
Topics discussed include: partial pressure of gases, composition of alveolar gas, transport of oxygen and carbon dioxide in the blood, buffer action of hemoglobin and seperated plasma, oxygenated whole blood and reduced blood, concepts of base excess and base deficit, and chemical regulation of respiration.
"Any reader who clearly understands the subject matter of this book will have a firm grounding in the principles of the subject; I find it the clearest text of this type that I have read."—British Journal of Hospital Medicine
"This little book is of great value to chemically trained physicians and medical students who want to get a clearer idea of the physiology of acid base chemistry in the blood."—The Journal of Gastroenterology
This new edition of Horace W. Davenport’s standard text takes into account different ways of looking at the problems of acid-base derived from new instrumentation. The exposition has been modified to allow the student to apply his understanding to other systems of description of the acid-base status. Although the pH system has been retained, there is increasing emphasis on the use of hydrogen ion concentration.
Topics discussed include: partial pressure of gases, composition of alveolar gas, transport of oxygen and carbon dioxide in the blood, buffer action of hemoglobin and seperated plasma, oxygenated whole blood and reduced blood, concepts of base excess and base deficit, and chemical regulation of respiration.
"Any reader who clearly understands the subject matter of this book will have a firm grounding in the principles of the subject; I find it the clearest text of this type that I have read."—British Journal of Hospital Medicine
"This little book is of great value to chemically trained physicians and medical students who want to get a clearer idea of the physiology of acid base chemistry in the blood."—The Journal of Gastroenterology
132 pages | 0.00 x 0.00 | © 1974
Committee on Publications in Biology and Medicine
Biological Sciences: Biochemistry
Table of Contents
Preface
1 What Happens in Blood
1.1 The Partial Pressure of a Gas
1.2 Composition of Alveolar Air
1.3 Carriage of Oxygen in the Blood
1.4 Carriage of Oxygen in the Blood by Physical Solution
1.5 Carriage of Oxygen in the Blood by Hemoglobin
1.6 The pH Scale
1.7 Buffer Action
1.8 Hemoglobin as a Buffer: The Titration Curve of Oxyhemoglobin
1.9 The Direct Combination of Carbon Dioxide with Hemoglobin: Carbamino Compounds
1.10 Hemoglobin as a Buffer: The Effect of Reduction
1.11 Carriage of Carbon Dioxide in the Blood: Qualitative Aspects
1.12 Carriage of Carbon Dioxide in the Blood: Quantitative Aspects
1.13 Fundamental Equations
1.14 Calculation of the Partition of Carbon Dioxide in Plasma
1.15 Calculation of the Partition of Carbon Dioxide in Whole Blood
1.16 The pH-Bicarbonate Diagram
1. f7 The Buffer Value of Separated Plasma and of Oxygenated Whole Blood
2 What Happens in a Person
2.1 The Slope of the Normal Buffer Line in Vitro and in Vivo
2.2 The Buffer Line of Reduced Blood and the Concept of Base Excess or Deficit
2.3 Estimation of Base Excess or Deficit
2.4 Normal Acid-Base Paths without Compensation
2.5 Normal Ranges
2.6 Chemical Regulation of Respiration
2.7 Respiratory Compensation for Metabolic Alkalosis or Acidosis
2.8 Renal Processes Responding to Acid-Base Changes
2.9 Renal Responses to Metabolic Alkalosis and Acidosis
2.10 Renal Compensation for Respiratory Alkalosis or Acidosis
2.11 Identification of Acid-Base Status
2.12 Clinical Example: Metabolic Acidosis
2.13 Clinical Example: Respiratory Alkalosis
3 Other Ways of Looking at the Problem
3.1 The pH-Log Pco2 Diagram
3.2 Determination of Acid-Base Status of Blood by Equilibration with Gas Mixtures of Known Pco2
3.3 Quantitation of the Metabolic Component: The Carbon Dioxide Combining Power
3.4 Quantitation of the Metabolic Component: Standard Bicarbonate
3.5 Quantitation of the Metabolic Component: The Base Excess Scale
Bibliography
1 What Happens in Blood
1.1 The Partial Pressure of a Gas
1.2 Composition of Alveolar Air
1.3 Carriage of Oxygen in the Blood
1.4 Carriage of Oxygen in the Blood by Physical Solution
1.5 Carriage of Oxygen in the Blood by Hemoglobin
1.6 The pH Scale
1.7 Buffer Action
1.8 Hemoglobin as a Buffer: The Titration Curve of Oxyhemoglobin
1.9 The Direct Combination of Carbon Dioxide with Hemoglobin: Carbamino Compounds
1.10 Hemoglobin as a Buffer: The Effect of Reduction
1.11 Carriage of Carbon Dioxide in the Blood: Qualitative Aspects
1.12 Carriage of Carbon Dioxide in the Blood: Quantitative Aspects
1.13 Fundamental Equations
1.14 Calculation of the Partition of Carbon Dioxide in Plasma
1.15 Calculation of the Partition of Carbon Dioxide in Whole Blood
1.16 The pH-Bicarbonate Diagram
1. f7 The Buffer Value of Separated Plasma and of Oxygenated Whole Blood
2 What Happens in a Person
2.1 The Slope of the Normal Buffer Line in Vitro and in Vivo
2.2 The Buffer Line of Reduced Blood and the Concept of Base Excess or Deficit
2.3 Estimation of Base Excess or Deficit
2.4 Normal Acid-Base Paths without Compensation
2.5 Normal Ranges
2.6 Chemical Regulation of Respiration
2.7 Respiratory Compensation for Metabolic Alkalosis or Acidosis
2.8 Renal Processes Responding to Acid-Base Changes
2.9 Renal Responses to Metabolic Alkalosis and Acidosis
2.10 Renal Compensation for Respiratory Alkalosis or Acidosis
2.11 Identification of Acid-Base Status
2.12 Clinical Example: Metabolic Acidosis
2.13 Clinical Example: Respiratory Alkalosis
3 Other Ways of Looking at the Problem
3.1 The pH-Log Pco2 Diagram
3.2 Determination of Acid-Base Status of Blood by Equilibration with Gas Mixtures of Known Pco2
3.3 Quantitation of the Metabolic Component: The Carbon Dioxide Combining Power
3.4 Quantitation of the Metabolic Component: Standard Bicarbonate
3.5 Quantitation of the Metabolic Component: The Base Excess Scale
Bibliography