This volume records the discussions held during the international seminar organized in November 2014 in Pisa by the Italian National Research Council (CNR) at the Institute for Computational Linguistics (ILC), Pisa, as part of the European Resaerch Council project ‘Greek into Arabic, Philosophical Concepts and Linguistic Bridges’. Generally, it advances the idea that the analysis and translation of texts, especially ancient ones, with the aid of an open-source software available online, must be developed in an infrastructural dimension in order to facilitate scientific collaboration. This approach, which is new to digital Humanities, and in particular to digital textual scholarship, derives from the flexibility and compatibility of the software created for the ERC project (G2A Web App). The value of the method is strengthened by the specific experiences described in the papers: the encounter of philology, computational linguistics, and computer technology paves the way to new research prospects not only for the historians of philosophy, such as the scholars who participate to the ERC project, but for all the fields of the humanities.