Cloth $80.00 ISBN: 9781861348982 Published May 2011 For sale in North and South America only
Paper $32.95 ISBN: 9781861348975 Published May 2011 For sale in North and South America only

An Introduction to Genetic Epidemiology

Edited by Lyle J. Palmer, Paul R. Burton, and George Davey Smith

An Introduction to Genetic Epidemiology
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Edited by Lyle J. Palmer, Paul R. Burton, and George Davey Smith

Distributed for Policy Press at the University of Bristol

256 pages | 6 3/4 x 9 1/2 | © 2011
Cloth $80.00 ISBN: 9781861348982 Published May 2011 For sale in North and South America only
Paper $32.95 ISBN: 9781861348975 Published May 2011 For sale in North and South America only
Genetic epidemiology is a very rapidly developing field that has acquired a central role in modern biomedical science. Until now there has been no comprehensive introductory text for students and academics who do not have specialised training in statistics or genetics. This book begins with a primer in human molecular genetics and then examines standard methods in population genetics and genetic epidemiology required for an adequate grounding in the field. Among much else, the book contains discussion of the public health aspects of the new genetics, and of epidemiological methods for studying genes and environmental factors in complex diseases.Written by leading international experts and supplemented by a glossary and in-chapter guides to further reading, this essential textbook will be widely welcomed by teachers and students on many courses internationally.
Contents
List of tables, figures and boxes
Notes on contributors
Acknowledgements
Introduction
      Lyle J. Palmer, Paul R. Burton, and George Davey Smith

1. Key concepts in genetic epidemiology
      Paul R. Burton, Martin D. Tobin, and John L. Hopper
2. Genetic linkage studies
      M. Dawn Teare and Jennifer H. Barrett
3. Genetic association studies
      Heather J. Cordell and David G. Clayton
4. Mapping complex disease genes using linkage disequilibrium and genome-wide association scans
      Lyle J. Palmer, Nicholas J. Timpson, David M. Evans, George Davey Smith, and Lon R. Cardon
5. A question of standards: what makes a good genetic association study?
      Andrew T. Hattersley and Mark I. McCarthy
6. Biobanks and biobank harmonisation
      Paul R. Burton, Isabel Fortier, Mylene Deschênes, Anna Hansell, and Lyle J. Palmer
7. Population health aspects of genetic epidemiology: genomic profiling, personalised medicine, and Mendelian randomisation
      George Davey Smith, Shah Ebrahim, Sarah Lewis, and Lyle J. Palmer

Glossary
Index
For more information, or to order this book, please visit http://www.press.uchicago.edu
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